Blood volume-based von Willebrand factor to prevent postpartum hemorrhage in von Willebrand disease.
نویسنده
چکیده
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منابع مشابه
Frequency Assessment of the H817Q (2451T→A) Variant of von Willebrand Gene in Individuals without Hemorrhagic Signs
Abstract Background and Aims: Von Willebrand disease is a bleeding disorder caused by quantitative or functional defects in von Willebrand factor. The disease is found in up to 1 percent of the population. The most common symptom is mucocutaneous bleeding. Recently, studies conducted on healthy people showed that the H817Q mutation that previously known to cause von Willebrand...
متن کاملVon Willebrand Factor and Von Willebrand Disease in Pregnancy – a Manageable Challenge
Repeated vaginal bleeding is a common complaint in outpatient obstetrical practice. Traditionally, it is treated with progesterone, without making an accurate etiological diagnosis. Hemorrhage during labor, delivery or postpartum period are considered obstetrical emergencies. Von Willebrand disease is one of the frequent causes for hereditary bleeding disorders; the diagnosis during pregnancy c...
متن کاملPostpartum Hemorrhage in Women with Von Willebrand Disease – A Retrospective Observational Study
INTRODUCTION von Willebrand disease (VWD) is a hereditary bleeding disorder, caused by a deficiency in the levels and/or function of von Willebrand factor (VWF). Women with VWD appear to be at increased risk of experiencing postpartum hemorrhage (PPH), though the levels of VWF increase during pregnancy. There is limited knowledge of how PPH is associated with the subtype of VWD, plasma levels o...
متن کاملGenetic Variations in Exon 3 of VWF Gene in Patients with Von Willebrand Disease (VWD) from South-West Iran
Abstract Background Von Willebrand disease (VWD) is an autosomally inherited bleeding disorder with the prevalence of 1% based on population studies. The disease phenotype is due to quantitative and structural/functional defects in Von Willebrand Factor (VWF) which is a glycoprotein with essential role as a carrier of FVIII in circulation and also it serves the function as hemostasis regulato...
متن کاملMultiple Sclerosis Diagnosed in a Woman With Von-Willebrand Disease: A Case Report
Background: Von-Willebrand Disease (VWD) is the most common inherited bleeding disorder with an autosomal inheritance pattern. Multiple Sclerosis (MS) is a neurological disease, causing neurodegeneration and demyelination of the central nervous system through autoimmune mechanisms, and is a major cause of non-traumatic disabilities in youths. Some studies have shown the higher plasma activity o...
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ورودعنوان ژورنال:
- Blood advances
دوره 1 11 شماره
صفحات -
تاریخ انتشار 2017